International Journal of Innovative Research in Health Science

Background: Polycystic Ovarian Syndrome (PCOS) is a common endocrine disorder among reproductive-age women and is associated with menstrual irregularities, metabolic disturbances, infertility, and psychological distress, all of which adversely affect quality of life (QOL). Objectives: To evaluate the effectiveness of nurse-led interventions on quality of life among women with PCOS. Methods: A quantitative quasi-experimental pretest–posttest control group design was adopted. Sixty women aged 25–35 years with clinically diagnosed PCOS were selected using purposive sampling from two hospitals in Krishnagiri, Tamil Nadu, India. Participants were assigned to experimental (n = 30) and control (n = 30) groups. Baseline QOL was assessed using a modified WHOQOL scale. Results: In the pretest, the majority of participants in both groups had poor QOL. Post-intervention, 53% of the experimental group achieved very good QOL compared with only 10% in the control group. The mean QOL score in the experimental group increased from 23.5 ± 7.87 to 40.75 ± 11.27 (t = 5.612, p < 0.001). Posttest comparison showed significantly higher scores in the experimental group than in the control group (40.75 ± 11.27 vs. 25.9 ± 9.84; t = 4.44, p < 0.05). Conclusion: Nurse-led interventions significantly improved the quality of life among women with PCOS and can be incorporated into routine management to enhance overall well-being.